474: David Eagleman | The Inside Story of the Ever-Changing Brain

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Episode Highlights
Neurons Competing
explains that our brains are composed of 86 billion neurons, each competing for territory and resources. This Darwinian competition among neurons is akin to trees in a forest vying for sunlight. He emphasizes that both genes and experiences shape our neural pathways, with experiences even altering gene expression through epigenetics 1 2.
The nature-nurture debate is dead. It's always both in ways that are untangleable.
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This interplay between genes and experiences creates a unique trajectory for each individual, highlighting the brain's adaptability.
Impact of Neglect
Neglect and lack of sensory input can have devastating effects on brain development. shares tragic examples, such as Romanian orphans who suffered cognitive deficits due to insufficient interaction. He explains that the brain prunes unused neural pathways, which can lead to irreversible damage if critical periods of development are missed 3 4.
Thousands of these children ended up with real cognitive deficits because they didn't get the right input.
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This underscores the importance of early sensory experiences in shaping a healthy brain.
Brain Plasticity
The brain's plasticity allows it to reallocate resources dynamically. describes how, for instance, blind individuals can repurpose their visual cortex for other senses like touch and hearing. This adaptability is harnessed in technologies like NeoSensory's wristband, which translates sound into tactile vibrations for the deaf 5 6.
The brain doesn't want any territory to lie fallow because this is really valuable stuff.
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Such innovations demonstrate the brain's remarkable ability to adapt and create new sensory experiences.
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