Norepinephrine and REM Sleep
A lack of norepinephrine release during REM sleep is crucial for memory processing, particularly in individuals with PTSD. When norepinephrine levels remain elevated, it prevents the necessary weakening of traumatic memories, causing them to feel fresh and immediate. This inability to downscale these memories can lead to maladaptive responses, hindering the ability to learn new contexts and move past trauma.In this clip
From this podcast

Huberman Lab
Dr. Gina Poe: Use Sleep to Enhance Learning, Memory & Emotional State | Huberman Lab Podcast
Related Questions
Explain in detail how changes in norepinephrine release during REM sleep are involved in PTSD and how elevated norepinephrine prevents the weakening of traumatic memories, hindering emotional processing and adaptation to new contexts, as discussed in the episode Dr. Gina Poe: Use Sleep to Enhance Learning, Memory & Emotional State | Huberman Lab Podcast and the clip Pgo Waves and Dreams.
Explain in detail how changes in norepinephrine release during REM sleep are involved in PTSD and how elevated norepinephrine prevents the weakening of traumatic memories, hindering emotional processing and adaptation to new contexts.