Can overproduction of the stress hormone, i.e. cortisol, be curbed with some nutritional supplements or pills?

Sources:

Certain nutritional supplements have been mentioned on the for their potential to help curb the overproduction of cortisol:

  • Ashwagandha: has spoken about using ashwagandha occasionally during periods of prolonged stress. It is known to buffer cortisol effectively, but he advises cycling it (i.e., taking it for a week or so and then stopping) rather than continuously using it. Chronic supplementation with ashwagandha can disrupt other hormonal and neurotransmitter pathways if used longer than about two weeks continuously 1.

  • Phosphatidylserine: While not personally used by , he discussed that Tim Ferriss has used phosphatidylserine to help blunt cortisol release, particularly in contexts of high rumination or stress 2.

  • Rhodiola Rosa: This supplement is a fatigue reducer that can help with managing cortisol levels. However, cortisol suppression isn't always beneficial, depending on the individual's physiological state and it has been suggested that Rhodiola Rosa is more of a modulator than a suppressor of cortisol 3.

    Reducing Cortisol

    Andrew discusses the use of ashwagandha as a potent inhibitor of cortisol, but warns against chronic supplementation due to potential side effects. He recommends consulting with a healthcare provider before adding or subtracting anything from your health regimen.

    Huberman Lab

    Understanding & Controlling Aggression | Huberman Lab Podcast #71
    1
    2
    3

It's very important to consult with a healthcare provider before adding any supplements to your regimen, as individual needs and reactions can vary. Additionally, it is wise to be cautious with the chronic use of any supplements designed to modulate cortisol due to potential side effects 1.

RELATED QUESTIONS