What is the best time of day to take whey protein supplement

The best time of day to take a whey protein supplement, particularly if you are focused on building or maintaining muscle, is early in the day. This timing supports better protein synthesis and muscle hypertrophy due to the enhanced expression of the BMAL gene, which regulates protein synthesis pathways within muscle cells.

Andrew Huberman recommends ingesting protein before 10:00 AM, ideally soon after the first hour of waking. This approach helps maximize muscle growth and maintenance more effectively compared to consuming protein later in the day 1 2.