Published Aug 4, 2025

How to Control Your Cortisol & Overcome Burnout

Andrew Huberman delves into cortisol regulation, offering strategies to optimize rhythms for improved energy, focus, and sleep. He discusses the role of exercise, nutrition, and burnout phases in managing cortisol levels to enhance well-being and performance.
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Episode Highlights

  • Cortisol Foods

    Certain foods can naturally boost cortisol levels, playing a significant role in managing energy and stress. highlights grapefruit and black licorice as two potent options. Grapefruit extends cortisol's presence in the bloodstream by inhibiting enzymes that break it down, while black licorice, through its compound glycyrrhizin, increases cortisol levels by inhibiting the enzyme 11 beta HSD 1 2.

    Grapefruit has a significant impact in inhibiting the enzyme that breaks down cortisol.

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    These foods can be particularly useful for those needing to elevate cortisol levels, but caution is advised to avoid excessive intake, especially later in the day.

       

    Low-Carb Effects

    Low-carbohydrate diets can influence cortisol rhythms, especially during the initial transition period. explains that while low-carb diets can initially increase cortisol levels, these levels typically normalize after about three weeks 3 4. This temporary increase aligns with the body's natural cortisol pattern, which peaks in the morning and declines by evening.

    For the first three weeks on that diet, you see a significant increase in cortisol.

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    If sleep quality is unaffected, the diet may be suitable, but introducing starchy carbohydrates in the evening could help manage cortisol levels for those experiencing sleep disturbances.

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