Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

Castleman's Battle

David C. Fajgenbaum faced a life-threatening battle with Castleman's disease, a rare condition that nearly claimed his life. He discovered that many existing drugs, already approved for other uses, could be repurposed to treat diseases deemed untreatable by the medical community 1. This revelation led him to establish EveryCure, a nonprofit dedicated to finding treatments for such diseases. Fajgenbaum shares a poignant story about a young patient, Joey, who was saved by the same drug that saved him, highlighting the potential of drug repurposing 2.

The drug I'm on is helping other people. It's not just this sort of one-off thing.

--- David C. Fajgenbaum

His journey underscores the importance of exploring unconventional medical paths and the potential of existing medications to save lives 3.

   

Family Support

Throughout his ordeal, David Fajgenbaum received unwavering support from his family, which played a crucial role in his recovery. His sister's encouragement during a particularly painful moment in the ICU exemplifies the power of emotional support 4. This familial strength was pivotal, as it provided him with the resilience needed to endure the excruciating pain and uncertainty of his condition. Fajgenbaum also reflects on a promise he made to his mother, who battled brain cancer, to dedicate his life to finding treatments for patients like her 5.

You can do anything for, like, one minute or one hour or one day.

--- David C. Fajgenbaum

This promise fueled his determination to overcome his illness and contribute to medical advancements.

   

Mindset & Resilience

David Fajgenbaum's mindset and resilience, shaped by his experiences as a college athlete, were instrumental in his fight against Castleman's disease. His athletic background instilled a drive and determination that mirrored the persistence needed to tackle his health challenges 6. Despite facing multiple near-death experiences and relapses, he maintained hope and continued to seek new treatments, demonstrating remarkable perseverance 7.

If these seven chemotherapies are working, how do we know there's not an eighth?

--- David C. Fajgenbaum

His gratitude for life and inquisitive nature allowed him to question existing medical practices and push for innovative solutions, ultimately leading to life-saving discoveries 8.