Reverse Aging & Reduce Inflammation with OneSkin’s Carolina Oliveira | 287 | Kelly LeVeque

Aging Causes

Aging is primarily the result of accumulated cellular damage over time. Carolina Oliveira explains that when we are young, our DNA repair systems efficiently manage damage, but as we age, these systems become overwhelmed, leading to mutations and the formation of senescent or "zombie" cells 1. These cells, unable to function properly, produce inflammatory signals that accelerate the aging process in surrounding healthy cells.

Zombie cells are like a bad apple in a basket, accelerating the aging of surrounding cells.

--- Carolina Oliveira

Environmental factors such as UV exposure and diet further exacerbate this damage, making it crucial to understand and mitigate these influences 1.

   

Zombie Cells

Zombie cells, or senescent cells, are central to the aging process due to their inflammatory secretions. Carolina Oliveira highlights that these cells impair collagen production and compromise the skin barrier, leading to visible signs of aging like wrinkles and sagging 2. By targeting and removing these cells, we can potentially restore skin to a healthier state.

Removing senescent cells allows healthy cells to proliferate normally, maintaining skin function.

--- Carolina Oliveira

Research at OneSkin focuses on developing peptides that specifically target and decrease these zombie cells, aiming to rejuvenate skin by reducing inflammation and enhancing collagen production 3.

   

Oxidative Stress

Oxidative stress is a major contributor to aging, exacerbated by environmental factors and lifestyle choices. Kelly LeVeque discusses how antioxidants can help neutralize oxidative stress, reducing DNA damage and the formation of senescent cells 4. Peptides developed by OneSkin aim to decrease inflammatory cytokines secreted by zombie cells, thus reducing inflammation and promoting skin health.

Antioxidants are crucial in preventing oxidative stress and subsequent DNA damage.

--- Kelly LeVeque

While antioxidants are essential, removing existing zombie cells remains vital for reversing aging signs and maintaining skin vitality 4.