What is the recommended glycine dosage?

Start with 3–5 grams of glycine orally at bedtime, especially if you’re having trouble settling down at night. Try it for a few nights; if you notice no effect, the suggested next step is to increase to 10 grams. At that dose, many people notice a calming effect and somewhat easier sleep onset; glycine is also described as supporting phase-two liver detoxification while you sleep. 1 2