How frequently can I do psychedelics like lsd, mdma or mushrooms?

There’s no established safe frequency for personal use; the one-to-three-week spacing mentioned applies to supervised psychedelic-therapy research, not a general-use recommendation. 1

• Frequency varies: The discussion distinguishes substances and contexts rather than giving one schedule for LSD, MDMA, and mushrooms. It describes therapy dosing sessions as typically spaced one, two, or three weeks apart across research sites. 1
• Therapeutic use: Research protocols involve preparation, a controlled setting and trained support, followed by integration; the therapy model may include multiple preparation and follow-up sessions. 2 3
• Risks and legality: Psychedelics can lead to difficult or harmful experiences, and may worsen problems such as psychosis or bipolar symptoms in susceptible people. The legal and regulatory context also differs by place. 4 5