NAC for colds

NAC may help ease cold congestion and may reduce influenza symptoms, but stronger randomized controlled trials are still needed to establish its preventive benefit. 1 2

• 1. Study result: One study reported clinically apparent flu in 25% of people taking NAC versus 79% taking placebo. 3
• 2. Doses described: For prevention, the cited dose was 1,200 mg daily, split into two 600 mg doses. For an existing cold, Huberman described taking 900 mg three times daily. 4 5
• 3. How it may help: NAC is a precursor to glutathione and acts as a mucolytic, loosening mucus to help relieve congestion. Huberman contrasted it with some decongestants, which can cause rebound congestion as they wear off. 6 7
• 4. Timing: Avoid taking NAC close to bedtime; increased mucus flow and post-nasal drip disrupted Huberman’s sleep. 8