How does it enhance cognition?
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Methylene blue enhances cognition through several mechanisms, primarily by improving mitochondrial function and neurotransmitter activity. Here are some key points discussed on the :
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Mitochondrial Function: Methylene blue acts as an oxygenator by increasing the ability of hemoglobin to carry oxygen. This boosts mitochondrial efficiency, which is crucial for overall cellular function, including in neurons, potentially enhancing cognitive tasks such as memory recall and mental clarity 1 2.
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Neurotransmitter Activity: It serves as a mild monoamine oxidase inhibitor (MAOI), which means it can extend the activity of neurotransmitters like serotonin in the brain. This action can lead to cognitive benefits by affecting mood and other cognitive processes 3.
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Rapid Onset and Combining Agents: The effects of methylene blue are relatively rapid, and when combined with caffeine and B vitamins, users report significant improvements in brain function. The recommended dosage is generally around 10 milligrams taken in the morning to harness its cognitive enhancing properties 2 3.
These properties make methylene blue an interesting nootropic, although it's crucial to use it responsibly and consider potential side effects, such as changes in urine color and consultation with healthcare providers 3.
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