NAD+: A Quantum Leap in Biohacking | 1122 | Dave Asprey

Optimal Timing

Understanding the optimal timing for NAD+ supplementation can significantly enhance its effectiveness. Dr. Gregory Kelly highlights that NAD levels in the blood tend to peak between late morning and early afternoon, suggesting that taking NAD+ supplements earlier in the day can improve metabolic health and energy levels 1. Dave Asprey adds that the timing of supplements like vitamin D and magnesium also plays a crucial role in aligning with our circadian rhythms 2.

The circadian timing of nutrients has been important for a long time.

--- Dave Asprey

This approach ensures that energizing supplements are taken when the body is most active, maximizing their benefits.

   

Clinical Trials

Clinical trials on NAD+ supplementation reveal promising results for boosting NAD levels. Gregory Kelly shares his personal experience with Qualia NAD+, noting a 156% increase in his NAD+ levels after 20 days of use 3. Other self-experimenters, like Bob Troya, also reported significant increases, with an average rise of 82% in a placebo-controlled study 3.

Compared to placebo, there was a significant increase in NAD with Qualia NAD.

--- Dr. Gregory Kelly

These findings suggest that oral supplementation can be as effective as IV treatments, offering a more economical and convenient option for enhancing cellular energy and longevity.

   

Comparing Supplements

Comparing different NAD supplements reveals both benefits and challenges. Dr. Kelly explains that Qualia NAD+ includes nicotinamide riboside, niacin, and niacinamide to support multiple pathways for NAD production 4. However, regulatory challenges have impacted the availability of NMN, a once-promising supplement, due to its reclassification by the FDA 5.

If I can get that 80 something percent increase by taking a multi-ingredient formula like Qualia NAD+, there's no point to taking NMN.

--- Dave Asprey

This comprehensive approach in Qualia NAD+ offers a balanced and effective solution for boosting NAD levels without the regulatory hurdles associated with NMN.