217. How to lose weight

Micronutrients

Paul Saladino emphasizes the critical role of micronutrients in maintaining satiety and preventing overeating. He argues that the Western diet, rich in seed oils and processed foods, leads to nutrient inadequacy, making people hungrier and more prone to overeating. Paul believes that ensuring an adequate intake of vitamins and minerals like zinc, magnesium, and selenium can help curb hunger and support sustainable weight loss 1.

If humans are not taking in an adequate array of micronutrients, they will continue to be hungry.

--- Paul Saladino

He also mentions the protein leverage hypothesis, suggesting that insufficient protein intake can drive overeating 1.

   

Seed Oils

Paul discusses the adverse effects of seed oils on satiety and hunger regulation. He explains that the high intake of linoleic acid, a common component of seed oils, can disrupt thyroid function and increase hunger by affecting brain signaling pathways 2.

These are excess calories that can affect signaling pathways in the differentiation of fat cells, that can make you hungrier at the level of your brain and your cannabinoid receptors.

--- Paul Saladino

Paul also highlights the lack of research on the negative impacts of polyunsaturated fatty acids, attributing this gap to the influence of pharmaceutical companies 2.